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Chapter 3 Components of acute venous red thrombus
1.Pathology of acute venous thrombus
Acute venous thrombus is characterized by easy degradation and autolysis. Delayed thrombolysis is effective on acute massive pulmonary embolism (PE); usually only low molecular heparin is used to dissolve thrombus in submassive PE. Interventional fragmentation is adopted to quickly lyse the massive thrombus and effectively recover the blood flow in the pulmonary artery when thrombolysis is contraindicated in patients with acute massive PE. However, the arterial thrombus lacks this kind of characteristics.
Acute venous thrombus is red thrombus, which is composed of red blood cells,platelets, white blood cells and plasma proteins under the microscope (Figure 3-1-1).
Figure 3-1-1 HE staining of venous thrombus. It is red thrombus, in which massive red blood cells and white blood cells with dark-brown nuclei are aggregated (HE staining, ×200).(International Journal Of Clinical And Experimental Medicine ,2015 , 8 (11) : 19804-19814)