React
React is a declarative and component-based JavaScript library for building user interfaces. Its declarative and modular nature makes it easy for developers to create and maintain reusable, interactive, and complex user interfaces.
Large applications that display a lot of changing data can be fast and responsive if built with React, as it takes care of efficiently updating and rendering just the right UI components when specific data changes. React does this efficient rendering with its notable implementation of a virtual DOM, setting React apart from other web UI libraries that handle page updates with expensive manipulations directly in the browser's DOM.
Developing user interfaces using React also forces frontend programmers to write well-reasoned and modular code that is reusable, easier to debug, test, and extend.
Check out resources on React at https://reactjs.org/.
Since all four technologies are JavaScript-based, these are inherently optimized for integration. However, how these are actually put together in practice to form the MERN stack can vary based on application requirements and developer preferences, making MERN customizable and extensible to specific needs.